SPR Sessions at PAS 2022

PAS 2022

April 21 – April 25

Please note all times are listed in Mountain time zone (MT)

Friday, April 22

2:30-4:00pm - APS SPR Joint Plenary: Reducing susceptibility to misinformation: COVID, Climate, and Conspiracies

APS/SPR Joint Presidential Plenary: Reducing susceptibility to misinformation: COVID, Climate, and Conspiracies

Friday, April 22, 2022
2:30 PM – 4:00 PM
Location: Four Seasons Ballroom 2-3

  • Moderator: David Keller
  • Presentation 1: Reducing susceptibility to misinformation: COVID, Climate, and Conspiracies
    Speaker: Kathleen Hall Jamieson
  • Presentation 2: State Politics & Public Health: A cautionary tale
    Speaker Michelle Fiscus
  • Presentation 3: It’s Not Politics. It’s Child Health.
    Speaker Judy Schaechter
  • Q & A Session: David Keller with Kathleen Hall Jamieson, Michelle Fiscus, and Judy Schaechter

The science of medicine offers tremendous opportunities to improve the health of children, but our ability to deliver on that promise may be thwarted by the blizzard of misinformation readily available to our patients and families. In this session, Dr. Kathleen Hall Jamieson of the Annenberg School at the University of Pennsylvania will explain how pediatricians can reframe the way in which we think about misinformation. She will show how we can create a “buffer” to misinformation by proactively providing background knowledge that translates the language of science into the language of the popular culture. She will be joined on this panel by Dr. Michelle Fiscus, pediatrician and former Tennessee vaccine chief in charge of the COVID-19 vaccine roll-out, and Dr. Judy Schaechter, President and CEO of the American Board of Pediatrics. They will describe how this approach can make sense of recent events in Tennessee (COVID vaccines), Florida (firearm safety) and nationally (climate change) and allow us to refocus our energy on the health of children and families.

6:15-7:15pm - APS SPR Journey’s Reception for Alumni & Current Participants

APS SPR Journeys Reception for Alumni & Current Participants (Invitation Only)

Friday, April 22, 2022
 6:15 PM – 7:15 PM
 Location: Convention Center: TBD

Saturday, April 23

7:00-8:00am - SPR Grant Writing 101 Program (Invitation Only)

SPR Grant Writing 101 Program

Saturday, April 23, 2022
7:00 AM – 8:00 AM US MT
Location: Hyatt Regency: Mineral Hall A

8:00-9:30am - The Role of Tax Credits in Achieving Child Health Equity

The Role of Tax Credits in Achieving Child Health Equity

Saturday, April 23, 2022
8:00 AM – 9:30 AM US MT
Location: Convention Center: 709/711

Chair(s)

  • Lois Lee, MD, MPH
    Boston Children’s Hospital, Harvard Medical School

10:00 AM–11:30am - Drug Pricing and Access to Medications: Impact on Child Health

Drug Pricing and Access to Medications: Impact on Child Health

Saturday, April 23, 2022 10:00 AM – 11:30 AM US MT
Location: Convention Center: 507

Chair(s)

  • Punita Ponda, MD
    Donald and Barbara Zucker School of Medicine at Hofstra/Northwell

11:30-12:30pm - SPR Regional Societies Business Meeting & Luncheon (Invitation Only)

SPR Regional Societies Business Meeting and Luncheon – By Invitation Only

Saturday, April 23, 2022

11:30 AM – 12:30 PM US MT
Location: Hyatt Regency: Centennial Ballroom E

Meeting of the officers of SPR, Midwest SPR, Western SPR, Southern SPR and Eastern SPR. By Invitation Only

1:00-2:30p - The State of Pediatric Research – Are We Still Meeting Today’s Academic Challenges?

The State of Pediatric Research – Are We Still Meeting Today’s Academic Challenges?

Saturday, April 23, 2022
1:00 PM – 2:30 PM US MT

Chairs:

  • Esther Speer, MD
    Stony Brook Children’s Hospital
  • Joyce Javier, MD, MPH, MS
    Children’s Hospital Los Angeles

Children have unique and rapidly changing health care needs including psychosocial and developmental processes. Resolving early life diseases and adverse experiences will have lifelong benefits. However, today’s pediatric researchers face many financial, regulatory, institutional, and career choice challenges. Among these are an increasingly competitive funding environment, characterized by declining federal pediatric research portfolio purchasing power and lack of commercial interest in children’s studies. Clinical trials involving pregnant women and minors require extra safety standards, further increasing costs and human resources. For many academic pediatricians, high clinical volume competes with their engagement in meaningful basic and clinical research. The resulting diminishing and aging workforce of pediatric physician-scientists has consequences for discoveries and available therapies. Most pediatric clinical trials registered in ClinicalTrials.gov were small-scale, single-centered, and not funded by industry or the federal government. Published pediatric studies comprise significantly less RCTs, systematic reviews, and therapeutic trials compared to adult studies. Consequently, approximately two thirds of all prescribed medications to children have insufficient evidence regarding their dosing, efficacy, and safety.
This session will highlight national trends concerning federal and non-governmental expenditures for children’s research, legislative and advocacy challenges, and opportunities. The speakers will discuss barriers facing pediatric therapeutic trials, as well as potential avenues to promote these trials such as the Best Pharmaceuticals for Children Act and the Institute for Advanced Clinical Trials for Children. Novel data-driven approaches to improve pediatric research infrastructure and productivity will be highlighted.
This session is endorsed by the Society for Pediatric Research and the SPR Advocacy Committee.

6:30-7:30pm - APS & SPR Joint Council Reception (Invitation Only)

APS & SPR Joint Council Reception By Invitation Only

Saturday, April 23, 2022
6:30 PM – 7:30 PM US MT
Location: Offsite: TBD

7:30-9:00pm - Joint SPR Research Showcase and Reception - Exclusively Sponsored by Abbott Nutrition

Joint SPR Research Showcase & Reception

Saturday, April 23, 2022
7:30 PM – 9:00 PM US MT
Location: Offsite: TBD

Meet SPR Leaders & Top Regional Talent.
Honor Our Collective Research Success.
Celebrate & Strengthen Our SPR Network & Collaborations.

Welcome and Introductions, Beth Tarini, SPR President, Michelle Gill, Ambassador, North American Regionals, and Lila Nolan, SPR Junior Section President

Midwest SPR ~ David McCulley, President
Presentations:
Zachary Vesoulis, Washington University in St. Louis
TJ Boly, University of Iowa

Western SPR ~ Henry Lee, President
Presentations:
Kameelah Gateau, Keck School of Medicine & University of Southern California
Alicia White, University of Colorado

Eastern SPR ~ Semsa Gogcu, ESPR Treasurer
Presentations:
Lynnlee Depicolzuane, Penn State College of Medicine
Shaili Amatya, Penn State College of Medicine

Southern SPR ~ Ravi Patel, President
Presentations:
Desalyn L. Johnson, University of Alabama at Birmingham
Colm Travers, University of Alabama at Birmingham

Exclusively Sponsored by:

Sunday, April 24

7:00-8:00am - SPR Advocacy Committee Meeting (Invitation Only)

SPR Advocacy Committee Meeting – By Invitation Only

Sunday, April 24, 2022
7:00 AM – 8:00 AM US MT
Location: Hyatt Regency: Agate AB

8:00-9:30am - SPR Presidential Plenary: Protecting an Endangered Species: SPR Supports Pediatric Researchers

SPR Presidential Plenary: Protecting an Endangered Species: SPR Supports Pediatric Researchers

Sunday, April 24, 2022
8:00 AM – 9:30 AM US MT

Moderator(s)

  • Kate Ackerman, MD, MBA
    University of Rochester School of Medicine and Dentistry

SPR welcomes all PAS attendees to this SPR Presidential Plenary where you will hear excellent scientific talks from several SPR awardees who are rising stars in pediatric research. A session you will not want to miss!


Introduction – Beth Tarini, MD, MS

SPR Award in honor of E Mead Johnson – Vijay Sankaran, MD, PhD, M.Phil “There Will Be Blood: Genetic Studies of Human Hematopoiesis”

Sponsored by:

SPR Young Investigator Award – Seth Rakoff-Nahoum, MD, PhD, “Bottom-up and Top-down Approaches to Understand the Host-Associated Microbiome”

SPR Bridging to Success Award – (2021) Catherine O. Buck, MD, “Metabolism and adiposity in moderate preterm infants”

SPR New Member Outstanding Science Award – Kristen Ogden, PhD “Understanding Rotavirus Outer Capsid Function through Gene Swapping and Adaptation”

10:00-11:30am - Are Human Rights a Fundamental Basis for Healthcare?

Are Human Rights a Fundamental Basis for Healthcare?

Sunday, April 24, 2022
10:00 AM – 11:30 AM US MT

Chair(s)

Luca Brunelli, MD, PhD
University of Utah School of Medicine

  • Luca Brunelli, MD, PhD, “Healthcare and human rights: time to take responsibility?”
  • Audrey R. Chapman, MA, StM, PhD, “What is a human rights-based approach to health care, implications for children”
  • Lisa Forman, LLB, MA, SJD, “The imperative of legal education for doctors and healthcare professionals”
  • Ranit Mishori, MD, MHS, FAAFP, “Physicians for human rights (PHR): a call to action”

Based on the Insights piece titled “Healthcare and Human Rights: A Reflection” published in March 2021 in Pediatric Research by the JEDI (Justice, Equity, Diversity, Inclusion) Committee of SPR, Dr. Luca Brunelli (University of Utah) will introduce the Session and provide some historical and sociological context regarding how the provision of healthcare has evolved in an international perspective, especially in the last 70 years (5 minutes). Dr. Audrey Chapman (University of Connecticut) will discuss what is a human rights-based approach to health care and what it means for doctors and health professionals to recognize a right to health. Dr. Chapman will also discuss the human rights of children and what they entail (25 minutes). Dr. Lisa Forman (University of Toronto) will speak to the imperative of legal education for doctors and health professionals. Dr. Forman will also speak about the implications of human rights violations for the medical system and utilize some examples from South Africa (25 minutes). Dr. Ranit Mishori (Georgetown University) will discuss why doctors and healthcare professionals should care about human rights and what are some clinical scenarios/encounters in which human rights violations may be related to a patient’s medical care. Dr. Mishori will also explain what some of the models are for educating doctors and health professional students about human rights and provide examples of how doctors and health professionals can engage in human rights research and advocacy.

Monday, April 25

8:00-9:30am - Geography of pediatric health: Using geospatial analysis tools in pediatric care

Geography of pediatric health: Using geospatial analysis tools in pediatric care

Monday, April 25, 2022
8:00 AM – 9:30 AM US MT

Chair(s)

  • Jennifer Klein, MD
    Children’s National Health System

    Attendees may have heard the public health axiom “One’s zip code is a better predictor of health than one’s genetic code,” but how is the impact of geographic location evaluated and how are the findings used to improve health outcomes? This session will explore the basic principles of geospatial analysis and provide examples of geospatial studies in pediatric health. Particular emphasis is placed on the use of geospatial analysis to address health disparities. Presenters will include Pediatricians and Epidemiologists who are using these cutting edge tools to learn more about their communities and their patient populations. Audience members of all levels of expertise are encouraged to attend – whether they are geospatial experts or simply want to learn more about this emerging field.

8:00-9:30am - Individualized Neonatal Care-Sex-Specific Approach Matters!

Individualized Neonatal Care-Sex-Specific Approach Matters!

Monday, April 25, 2022
 8:00 AM – 9:30 AM US MT

Chair(s)

  • Pradeep Alur, MD
    University of Mississippi Medical Center

The biological differences between the sexes manifest early during fetal life. The crown-rump length is larger in male fetuses compared to females in the first trimester. The use of sex-specific growth charts for preterm infants allows us to wonder if growth rates are sex specific, then their nutritional requirements would also be different. Sex differences in breast milk composition are noted in humans.
A recent study showed that infants receiving red blood cell transfusion from female donors had a lower risk of death or serious morbidity.
There are sex differences in the outcomes associated with hypoxic-ischemic encephalopathy, with males having poorer neurodevelopmental outcomes with a similar degree of HIE. Preliminary evidence shows that although caffeine following preterm HI benefits both sexes, reductions in microglial activation are seen in males only, suggesting alternate mechanisms of therapeutic action in females.
Dr. Ojeda: Discuss the sex-specific influence of maternal conditions and metabolic derangement such as hypoglycemia.
Dr. Alur: Sex Differences in Nutritional intake in late Preterm Infants and breast milk composition and the sex differences in neonatal outcomes, such as respiratory outcomes.
Dr. Fitch and Rosenkrantz: Discuss sex differences in microglial activation following caffeine treatment in neonatal hypoxia-ischemia with emphasis on neonatal vulnerability to and recovery from neurologic insult.
Dr. Hussain: Discuss sex-specific pharmacological effects in the neonates-for example, sex specific effects of prophylactic indomethacin on IVH.
We believe that awareness about sex-specific analysis of the data in all the neonatal studies may help us understand the therapeutic options better.

10:00-11:30am - SPR Presidential Plenary: “Transforming the Culture of Pediatric Research: We Are the Problem and the Solution”

SPR Presidential Plenary: Transforming the Culture of Pediatric Research: We Are the Problem and the Solution

Monday, April 25, 2022
10:00 AM – 11:30 AM US MT
Location: Convention Center: Four Seasons Ballroom 4

Chair

  • Kate G. Ackerman, MD, MBA
    University of Rochester School of Medicine and Dentistry

Introduction – Beth A. Tarini, MD, MS

Invited Speaker – Damon Williams, PhD – “Diversity, Equity, and Inclusion in a Post-Pandemic World: Renewal, Allyship, and the Imperatives of Leadership”

10:00-11:30am - Workshop: Addressing Dual Loyalty in Healthcare through a Human Rights Framework

Addressing Dual Loyalty in Healthcare through a Human Rights Framework

Monday, April 25, 2022
10:00 AM – 11:30 AM US MT
Location: Convention Center: 207

Co-Leader(s)

  • Luca Brunelli, MD, PhD
    University of Utah School of Medicine
  • Lisa Forman, LLB, MA, SJD
    University of Toronto, Ontario, Canada
  • Audrey Chapman, MA, StM, PhD
    UConn School of Medicine
  • Ranit Mishori, MD, MHS, FAAFP
    Georgetown University School of Medicine
  • Joe Kaempf, MD
    Providence Women and Children’s Services

“Dual loyalty” can be a problem for doctors and healthcare providers in any setting: duties to patients and society can conflict with obligations to employers (government, military, correctional facilities, large healthcare system) or even personal financial interests. Although these concepts can be taught to medical and healthcare students as a warning before they begin their careers, innumerable opportunities for “failure” have occurred throughout the history of medicine. Moreover, when a doctor or healthcare provider’s paycheck or job security derive from unproven or questionable clinical practices or from a prison operator or government carrying out policies that might arm patients, the conflict becomes all the more severe. Doctors and healthcare providers have in the past compromised themselves by enabling or even participating in practices like the administration of unnecessary medications, or by signing off on punishments. Lapses of omission are also a risk, where providers may recognize clear signs of abuse but neither record nor report them lest they jeopardize their own job security. This workshop will provide an opportunity to participate in three real life scenarios in which doctors and healthcare providers might find themselves entangled during the exercise of their profession. We will also discuss the legal and ethical knowledge necessary to overcome these challenges and hopefully better fulfill the calling of the medical profession toward our patients and society. Finally, we will explore possible “next steps” such as research, educational, and advocacy activities which participants could pursue to address some of the challenges discussed in the Workshop.

11:30-1:00pm - Eat. Greet. Celebrate: SPR Awards & New Member Reception

Eat. Greet. Celebrate: SPR Awards and New Member Reception

Monday, April 25, 2022
11:30 AM – 1:00 PM US MT
Location: Convention Center: TBD

Celebrate the achievements of the SPR Award Recipients and welcome the SPR New Members.

1:00-2:30pm - Workshop: Achieving Diversity in Pediatric Research: The Only Way to External Validity

Achieving Diversity in Pediatric Research: The Only Way to External Validity

Monday, April 25, 2022
1:00 PM – 2:30 PM US MT
Location: Convention Center: 207

Leader

  • Joyce Javier, MD, MPH, MS
    Children’s Hospital Los Angeles

Co-Leader

  • Nathalie Maitre, MD, PhD
    Emory University School of Medicine, United States

In this ‘how-to” workshop, presenters will share lessons learned from using community based participatory research and stakeholder engagement to increase participation of underrepresented populations in pediatric research. Dr. Joyce Javier will share to current state of the representation of diverse populations in clinical trials, the barriers and facilitators to recruiting minority populations, including the impact of racism, and examples from her own research addressing mental health during COVID-19. Digital stories by parent and youth research participants will also be shared as examples to outreach to diverse populations. Dr. Nathalie Maitre will share lessons learned from using parent engagement to ensure participation of diverse populations in pediatric clinical trials. Attendees will be encouraged to bring their own strategies and questions regarding how to achieve diversity in pediatric clinical trials. Case studies will also be presented to highlight practical strategies to achieve diversity in pediatric clinical trials. This workshop has been approved by the Society for Pediatric Research and Dr. Lina Chalak, from the PAS Planning Workgroup for SPR. It also falls in line with two of the PAS 2022 Highlighted Themes, Racism in Research and Medical Care and Managing the Pediatric Mental Health Crisis.

1:00-2:30pm - Pediatric Research: The emerging role of artificial intelligence, big data analysis and precision medicine in Pediatrics

Pediatric Research: The emerging role of artificial intelligence, big data analysis and precision medicine in Pediatrics.

Monday, April 25, 2022
1:00 PM – 2:30 PM US MT

Chair(s)

  • Cynthia Bearer, MD, PhD
    Case Western Reserve University School of Medicine

  • Brian Stansfield, MD
    Medical College of Georgia at Augusta University

The significance of the role of Artificial Intelligence (AI) applications in Pediatric Medicine such as machine learning, deep learning, and cognitive computing is emerging. Big data are extremely large datasets. Examples are minute-to-minute monitoring of vital signs, “omics” data, (e.g., genomics, metabolomics, and proteomics), environmental and lifestyle-related factors, socio-demographics, and data from standardized electronic health records (EHRs) or precision medicine platforms. Big data analysis by AI may facilitate identification of novel genotypes or phenotypes leading to personalized, targeted therapy, support clinical decision tools and identify unknown risk factors for childhood diseases.
The presentations in this session will be interdisciplinary in character, span multiple areas of pediatric subspecialties and presenters will range from early career to senior status.

Other Noteworthy Events

Friday, April 22

4:30 PM – 6:15 PM - PAS Opening General Session, Debbie Anagnostelis Keynote Speakers, and Joseph St. Geme Leadership Award

PAS Opening General Session, Debbie Anagnostelis Keynote Speakers, and Joseph St. Geme Leadership Award

Friday, April 22, 2022
4:30 PM – 6:15 PM
Location: Convention Center – Bellco Theatre

  • Introduction: Patrick Brophy, MD, PAS 2022 Program Chair
  • Debbie Anagnostelis Keynote Speakers:
    Grace M. Lee, MD MPH, Associate Chief Medical Officer for Practice Innovation, Stanford Children’s Health, Professor of Pediatrics, Stanford University School of Medicine
  • Shaquita L. Bell, MD, Senior Medical Director, Odessa Brown Children’s Clinic, Clinical Associate Professor
  • O.N. Ray Bignall II, MD, FAAP, FASN, Assistant Chief Diversity and Health Equity Officer, Nationwide Children’s Hospital, Director of Kidney Health Advocacy and Community Engagement, Division of Nephrology and Hypertension, Assistant Professor

Saturday, April 23

6:30–9:00pm - A Joint Session of the Neonatal Hemodynamics Club and the Lung Club

A Joint Session of the Neonatal Hemodynamics Club and the Lung Club

Saturday, April 23, 2022
6:30 PM – 9:00 PM
Location: Sheraton: Grand Ballroom

Chair(s)

  • Patrick McNamara, MB BCH BAO MSC
    Division Chief, Neonatal Medicine
    Pediatrics
    University of Iowa Roy J. and Lucille A. Carver College of Medicine
  • Martin Kluckow, MBBS PHD
    Professor
    Neonatology
    Sydney University

The Neonatal Hemodynamics Club addresses clinically relevant topics in neonatal-perinatal medicine with a special focus on developmental cardiovascular physiology and neonatal hemodynamics. The topic for 2022 will explore the variation in hemodynamic phenotypes in congenital diaphragmatic hernia and the importance of characterizing the biologic contributors to pulmonary vascular disease when optimizing cardiovascular care. Our two speakers will review the biophysiology of pulmonary hemodynamics and heart function in the setting of congenital diaphragmatic hernia, appraise the role of comprehensive echocardiography in defining physiologic phenotypes, and highlight opportunities for clinical innovation. There will be time set aside for audience questions and discussion to allow the audience to interact with our expert speakers.

Monday, April 25

7:00-8:00am - Pediatric Policy Council Legislative Breakfast: Public Policy Challenges and Opportunities for LGBTQ Youth

Pediatric Policy Council Legislative Breakfast: Public Policy Challenges and Opportunities for LGBTQ Youth

Monday, April 25, 2022
7:00 AM – 8:00 AM 
Location: Convention Center: 201/203

Chair

  • Shetal Shah, MD
    Maria Fareri Children’s Hospital at Westchester Medical Center
Advocates have made historic progress in recent decades advancing legal protections for the LGBTQ community. However, LGBTQ youth continue to experience disparate health outcomes in comparison to their peers and face barriers to achieving optimal health and well-being. Furthermore, there is an ongoing, coordinated effort at the state level to discriminate against transgender and gender-diverse youth by enacting legislation contrary to the guidance of professional medical organizations that bans lifesaving gender-affirming care and perpetuates discrimination and stigma through harmful policies. These efforts threaten significant harm to this population, and it is critical to engage elected officials to ensure public policy advances health equity for LGBTQ youth. This session will focus on opportunities to promote the health and well-being of LGBTQ youth in the current political environment. It will review the LGBTQ child health policies being debated and explain the impact of these policies on young people. Mark Del Monte, JD, chief executive officer and executive vice president at the American Academy of Pediatrics, and Shetal Shah, MD, chair of the Pediatric Policy Council will be joined by an LGBTQ advocate to offer commentary and engage the audience in dialogue on these critical public policy issues.