Matthew Taylor, MD

Matthew D. Taylor, MD, is an Associate Professor of Pediatrics in Critical Care Medicine at Cohen Children’s Medical Center and Assistant Professor of Molecular Medicine and the Institute for Molecular Medicine at the Feinstein Institutes for Medical Research. Dr. Taylor started his research career in medical school at the University of Pittsburgh and began focusing on the role of prior infection in modulating severe inflammation and organ dysfunction during residency and fellowship at the Children’s Hospital of Pittsburgh and the Children’s Hospital of Philadelphia respectively.

Dr. Taylor focuses on the role of T cell immune memory and T cell activation on the body’s response to severe inflammation. Through funding from an NIGMS K08 and the Thrasher Fund for Pediatric Research, Dr. Taylor has established that combined CD4 and CD8 T cell memory alter both the innate immune response and the organ dysfunction associated with the cecal ligation and puncture model of sepsis. He has an active laboratory using both murine models and human clinical samples and ongoing studies investigating how T cells and innate immune cells interact to promote ongoing inflammation and organ dysfunction in sepsis. He was recently awarded and NIGMS R35 ESI MIRA to continue work into how the sepsis-associated immune response changes as we age from the neonatal period into adulthood, how T cell interactions with the innate immune response shape sepsis-associated organ dysfunction and how the renin-angiotensin-aldosterone system alters innate and T cell responses to sepsis.