Influenza With and Without Oseltamivir Treatment and Pediatric Neuropsychiatric Events

James W. Antoon, MD, PhD, MPH, recently published an original investigation in JAMA Neurology on the use of the influenza antiviral oseltamivir associated with serious neuropsychiatric events. Dr. Antoon is an Assistant Professor of Pediatrics, Hospital Medicine at the Vanderbilt University Medical Center and Pediatric Hospitalist at Monroe Carell Jr. Children’s Hospital at Vanderbilt.

James W. Antoon, MD, PhD, MPH
James W. Antoon, MD, PhD, MPH
SPR Member
Influenza With and Without Oseltamivir Treatment and Neuropsychiatric Events Among Children and Adolescents

Question  Is the use of the influenza antiviral oseltamivir associated with serious neuropsychiatric events?

Findings  In this cohort study, the risk of serious neuropsychiatric events was lowest during periods without influenza. During influenza periods, treatment with oseltamivir was associated with a reduced risk of serious neuropsychiatric events compared with influenza periods without oseltamivir treatment.”

doi:10.1001/jamaneurol.2025.1995

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