Person holding an award certificate and a sign reading “SPR Awardee” in front of a backdrop with repeated Society for Pediatric Research logos at a Pediatric Academic Societies 2022 meeting.

Fellows’ Basic Research Awards

The Fellows’ Basic Research Awards are presented annually by the Society for Pediatric Research® (SPR) to honor fellows engaged in pediatric basic research. This award encourages pediatricians-in-training to pursue careers in academic pediatrics.

Recipients are selected based on the quality of work in basic research, as presented in abstracts submitted to the Pediatric Academic Societies (PAS) Meeting.

Awards

Five recipients are selected annually:
Two Basic Research Awards
One David G. Nathan Award
Two Basic Research Awards, sponsored by the SPR Emerging to Established (E2E) Section

All award recipients are chosen from the general category of SPR Fellows’ Basic Research Awards applications.

Group of five individuals standing in front of a backdrop with repeated Society for Pediatric Research logos; one person holds an award certificate and a sign reading “SPR Awardee,” while others wear conference badges and lanyards.

Fellows’ Basic Research Award

Eligibility Criteria

Be a fellow-in-training (PhD post-doctoral fellows do not qualify)
Submit and present the abstract during the PAS Meeting prior to the completion of fellowship
Complete the online application form and submit their abstract and supplemental materials by the abstract submission deadline
The applicants need to describe their contribution to the project when asked to provide “brief description of the work performed”
The abstract must be basic research
First authorship on an abstract submitted to the PAS Meeting; the abstract must be accepted for presentation at the upcoming PAS Meeting to be considered
The recipient must present the study at the PAS Meeting

Applications that do not meet the conditions stated above will not be considered for the awards. The accuracy of your abstract and application is the applicants’ responsibility. Please proofread carefully before submitting. After submission, no corrections will be permitted. By submitting, you approve the accuracy of your abstract and application.

Current Recipients

I am a second-year clinical fellow in the Neonatal-Perinatal Medicine Fellowship at the University of Miami Miller School of Medicine/Jackson Health System. To deepen my understanding of the pathogenesis of Bronchopulmonary dysplasia (BPD), I pursued a basic science research project under Dr. Shu Wu, focusing on the critical roles of inflammasome cascades in hyperoxia-induced lung injuries in neonatal mice.

Under Dr. Wu’s guidance, I spearheaded the investigation into the role of apoptosis associated speck-like protein containing a caspase recruitment domain (ASC) in BPD and the effects of IC100, a humanized anti-ASC antibody in preventing BPD in hyperoxia-induced mouse models. My first objective was to determine if hyperoxia activates ASC speck formation, which is required for inflammasome activation. I exposed ASC-citrine reporter mice, expressing ASC fusion protein with a C-terminal Citrine (fluorescent GFP isoform) to room air (RA) or 85% oxygen (O2) from postnatal day (P) 1 to P14, and then dissected the lung on P14, and prepared tissue sections for examination of ASC specks. I found that O2-exposed lungs had strong signals for ASC specks and BPD-like pathology, suggesting the activation of inflammasomes.

I then conducted experiments to assess the efficacy of IC100 in preventing hyperoxia-induced BPD. I randomized newborn mice to RA with placebo, RA with IC100 intraperitoneal injection, 85% O2 with placebo, and 85% O2 with IC100 intraperitoneal injection. On P14, I dissected the lung from these mice, assessed lung structures by radial alveolar count (RAC), and measured lung inflammation by counting macrophage infiltration in the alveolar airspace. I found that hyperoxia exposure reduced alveolarization and increased lung inflammation; however, IC100 treatment improved alveolarization and reduced lung inflammation in hyperoxia-exposed lungs. These results highlight the critical role of ASC in the pathogenesis of BPD and suggest that IC100 may have the potential to treat preterm infants from developing BPD.

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Noor Mehandi, MD

University of Miami Miller School of Medicine

Dr. Anusha Mopuri has been recognized for her innovative research in neonatal respiratory medicine, where she developed a novel approach using aerosolized human mesenchymal stem cell–conditioned media to prevent CPAP-induced airway hyperreactivity. Her work bridges basic science and clinical application, aiming to improve long-term respiratory outcomes in preterm infants.

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Anusha Mopuri, MBBS, MD

UH Rainbow Babies and Children’s Hospital

2024 | Betty Pham, MD, MS, UC San Diego/Rady Children’s of San Diego, CA
2024 | Michael Smith, MD, University of California, San Francisco, CA
2024 | Jingshing Wu, MD, PhD, University of California, San Francisco, CA
2023 | Aaron Bodansky, MD, UCSF, San Francisco, CA
2023 | Naomi Pode-Shakked, MD, PhD, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH
2022 | Naga Venkata Divya Challa, University of Miami, Miami, FL
2022 | Buyan-Ochir Orgil, The University of Tennessee Health Science Center, Memphis, TN
2022 | Nneka Ugwu, St. Christopher’s Hospital for Children, Philadelphia, PA
2021 | Jo Duara, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA
2021 | Ahmed Elsaie, Baylor College of Medicine, Houston, TX
2021 | Anam Amin Mendha, University of Miami School of Medicine, Miami, FL
2020 | Amelia Freeman, University of Alabama at Birmingham, Birmingham, AL
2020 | Oluwabunmi Olaloye, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA
2020 | Matthew Douglass, University of Utah, Salt Lake City, UT
2019 | Anum Ali, University of Miami, Miami, FL
2019 | Scott Gordon, Children’s Hospital of Philadelphia, Philadelphia, PA
2019 | Kent Willis, MD, The University of Tennessee Health Science Center, Memphis, TN
2018 | Abbie Bauer, University of Washington
2018 | Steven J. Jonas, University of California, Los Angeles (UCLA)
2018 | Kathleen Schwabenbauer, Children’s Hospital of Pittsburgh of UPMC
2017 | Keyur Donda, University of Miami Miller SOM, Miami, FL
2017 | Mohan Kumar Krishnan, University of South Florida, Tampa, FL
2017 | Laurel Truscott, UCLA
2016 | Keri A. Drake, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH
2016 | Jennifer Sucre, UCLA, Los Angeles, CA
2016 | Emir Tas, Children’s Hospital of Pittsburgh of UPMC, Pittsburgh, PA
2015 | David B. Frank, The Children’s Hospital of Philadelphia, Philadelphia, PA
2015 | Kok Lim Kua, University of Iowa, Iowa City, IA
2015 | Oded Volovelsky, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH
2014 | Rebecca Johnson, University of California, San Francisco, CA
2014 | Aparna Patra, Women & Infants Hospital of Rhode Island, Providence, RI
2014 | David P. Sparling, Columbia University Medical Center, New York, NY
2013 | Charitharth Vivek Lal, University of Texas at Southwestern Medical Center, Dallas, TX
2013 | Shelley Drummond, University of Miami Miller School of Medicine, Miami, FL
2012 | Claire Bocchini, Baylor College of Medicine, Houston, TX
2012 | Shaowei Chen, Tulane University Health Sciences Center, New Orleans, LA
2012 | Durga Singer, University of Michigan, Ann Arbor, MI
2011 | Molly K. Ball, Northwestern University Feinberg School of Medicine, Children’s Memorial Hospital, Chicago, IL
2011 | Levi Funches, Jr., Washington University School of Medicine, St. Louis, MO
2011 | Anne-Cecile Huby, Heart Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH
2010 | Thomas D. Arnold, University of California, San Francisco, CA
2010 | Julie Mirpuri, Emory University, Atlanta, GA
2010 | Francheyska Silfa Mazara, Floating Hospital for Children at Tufts Medical Ctr, Boston, MA
2009 | Jennifer R. Desireddi, Northwestern University, Feinberg School of Medicine, Chicago, IL
2009 | Sallie R. Permar, Children’s Hospital Boston / Harvard Medical School, Boston, MA
2009 | Laurie Steiner, Yale University, New Haven, CT
2008 | Alan Kenny, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH
2008 | Margaret Moriarty, University of Colorado at Denver HSC, Aurora, CO
2008 | Keiji Tanigaki, University of Texas Southwestern Medical Center, Houston, TX
2007 | John T. Benjamin, University of Alabama at Birmingham, Birmingham, AL
2007 | Darren Bridgewater, The Hospital for Sick Children, Toronto, ON, Canada
2007 | Lily Chao, University of California, Los Angeles, CA
2006 | Camille Fung, David Geffen School of Medicine, Los Angeles, CA
2006 | Michael Hunter, Yale University School of Medicine, New Haven, CT
2006 | Enkhsaikhan Purevjav, Baylor College of Medicine, Houston, TX
2005 | Ophir Klein, University of California, San Francisco
2005 | Kartik Krishnan, National Cancer Institute, Bethesda, MD
2005 | Mousumi Moulik, Baylor College of Medicine, Houston, TX
2004 | Kurt J. Griffin, National Institute of Child Health and Human Development, NIH, Bethesda, MD
2004 | Kimihiko Oishi, Mount Sinai School of Medicine, New York, NY
2004 | Lawrence M. Rhein, Children’s Hospital, Boston, MA
2003 | Gina-Marie Barletta, University of Michigan, Ann Arbor, MI
2003 | Christina M. Coughlin, Univ. of PA, Children’s Hospital, Philadelphia, PA
2003 | David Motto, University of Michigan, Ann Arbor, MI
2002 | Yair Anikster, National Institute of Health, Bethesda, MD
2002 | David G. Soergel, Johns Hopkins University School of Medicine, Baltimore, MD
2002 | Marco Tartaglia, Mount Sinai School of Medicine, New York, NY
2001 | Patrick D. Brophy, Mott Children’s Hospital/University of Michigan, Ann Arbor, MI
2001 | So Young Lee, Stanford University School of Medicine, Palo Alto, CA
2001 | Lawrence S. Prince, University of Iowa College of Medicine, Iowa City, IA
2000 | Christopher E. Belcher, Stanford University, Stanford, CA
2000 | Elif Erkan, Montefiore Medical Center, Bronx, NY
2000 | Syed Zaidi, The Hospital for Sick Children, Toronto, Canada
1999 | Vernat J. Exil, Washington University School of Medicine, St. Louis, MO
1999 | Laura Haneline, Indiana University School of Medicine, Indianapolis, IN
1999 | Gerardo Jimenez-Sanchez, Johns Hopkins Univ. School of Medicine, Baltimore, MD
1998 | Kathleen S. Crowley, Wake Forest Univ. School of Medicine, Winston-Salem, NC
1998 | John A. Martignetti, Mount Sinai School of Medicine, New York, NY
1997 | John M. Dagle, University of Iowa, Iowa City, IA
1997 | Edna E. Mancilla, National Institutes of Health, Bethesda, MD
1997 | Hideki Nishimura, Vanderbilt University School of Medicine, Nashville, TN
1996 | Peter N. Bowers, Yale School of Medicine, New Haven, CT
1996 | Cheryl Gale, University of Minnesota, Minneapolis, MN
1996 | Tao Wang, Johns Hopkins University, Baltimore, MD
1995 | Lilly Cheng Immergluck, University of Chicago, Wyler Children’s Hospital, Chicago, IL
1995 | Fumio Niimura, Vanderbilt University Medical Center, Nashville, TN
1995 | Deepak Srivastava, Anderson Cancer Center, Dallas, TX
1994 | Micahel Apkon, Yale University, New Haven, CT
1994 | Mukund G. Dole, University of Michigan Medical School, Ann Arbor, MI
1994 | Christaine Theda, Johns Hopkins Hospital School of Medicine, Baltimore, MD
1993 | Michael Cappello, Yale University School of Medicine, New Haven, CT
1993 | Steven A.Dekowski, University of Iowa, Iowa City, IA
1993 | D. Dunbar Ivy, University of Colorado School of Medicine, Denver, CO
1992 | Prasad Devarajan, Yale University, New Haven, CT
1992 | Han-Wook Yoo, Mount Sinai School of Medicine, New York, NY
1991 | Catherine M. Bendel, University of Minnesota, Minneapolis, MN
1991 | Charmian A. Quigley, University of North Carolina, Chapel Hill, NC
1991 | Lisa A. Schimmenti, Yale University School of Medicine, New Haven, CT

David G. Nathan Award in Basic Research

Established in 2000 by colleagues, trainees, and friends of Dr. David G. Nathan, the David G. Nathan Award in Basic Research honors his achievements in every aspect of academic pediatrics. The recipient is selected among the SPR Fellows’ Basic Research Award applicants whose abstract has been accepted for a platform session.

This award must be applied for at the time of PAS abstract submission.

Eligibility Criteria

Be a fellow-in-training (PhD post-doctoral fellows do not qualify)
Submit and present the abstract during the PAS Meeting prior to the completion of fellowship
Complete the online application form and submit their abstract and supplemental materials by the abstract submission deadline
The applicant needs to describe their contribution to the project when asked to provide “brief description of the work performed”
The abstract must be basic research
First authorship on an abstract submitted to the PAS Meeting; the abstract must be accepted for presentation at the upcoming PAS Meeting to be considered
The recipient must present the study at the upcoming PAS Meeting

Applications that do not meet the conditions stated above will not be considered for the awards. The accuracy of your abstract and application is the applicants’ responsibility. Please proofread carefully before submitting. After submission, no corrections will be permitted. By submitting, you approve the accuracy of your abstract and application.

Current Recipient

Developing new and effective therapies for preterm infants remains challenging, partly due to limited knowledge of how preterm birth alters normal immune system development. During my Neonatal-Perinatal Medicine fellowship, I aimed to precisely characterize how the preterm immune system evolves over time and in response to diseases of prematurity.

Person wearing glasses, a dark suit, white shirt, and light blue tie, standing against a plain gray background.

Benjamin Fensterheim, MD, PhD

Children’s Hospital of Philadelphia

2024 | Rameshwar Rao, MD, PhD, University of California, Davis
2023 | Ellen Schill, MD PhD, Washington University, St. Louis, MO
2022 | Amanda J. Clark, University of Texas Southwestern, Dallas, TX
2021 | Snehashis Hazra, University of Alabama at Birmingham, Birmingham, AL
2020 | Hua Sun, Boston Children’s Hospital, Harvard Medical School, Boston, MA
2019 | Viral Jain, MD, Cincinnati Children’s Hospital, Cincinnati, OH
2018 | Julie Nogee, Washington University School of Medicine, St. Louis, MO
2017 | Laura Jackson, Children’s Hospital of Pittsburgh of UPMC, Pittsburg, PA
2016 | Shawndip K. Sen, UT Southwestern Medical Center, Dallas, TX
2015 | Jason Boehme, University of California, San Francisco, CA
2014 | Elizabeth C. Swanson, University of Minnesota Medical School, Minneapolis, MN
2013 | Sujana S. Gunta, University of California, San Diego, CA
2012 | Grzegorz Nalepa, Indiana University, Indianapolis, IN
2011 | Misty Lynn Good, Children’s Hospital of Pittsburgh, PA
2010 | Ulrike Mietzsch, University of Texas Health Science Center, Houston, TX
2009 | No Award Given
2008 | Johannes Zakrzewski, Memorial Sloan Kettering Cancer Center, NY, NY
2007 | Kristina A. Cole, Children’s Hospital of Philadelphia, PA
2006 | Su Young Kim, National Institutes of Health, Bethesda, MD
2005 | Mwe Mwe Chao, The University of Michigan, Ann Arbor, MI
2004 | Benjamin S. Braun, University of California, San Francisco, CA
2003 | Marco Tartaglia, Mount Sinai School of Medicine, New York, NY
2002 | Valerie I. Brown, Children’s Hospital of Philadelphia, Philadelphia, PA
2001 | Jenny M. Kim, Abramson Research Center, Philadelphia, PA
2000 | Lisa Wang, Baylor College of Medicine, Houston, TX

SPR Basic Research Awards for Fellows, sponsored by the SPR Emerging to Established (E2E) Section

Established in 2013, the SPR Basic Research Awards for Fellows, sponsored by the SPR Emerging to Established (E2E) Section, recognizes outstanding basic research conducted by fellows. The recipient is selected among the SPR Fellows’ Basic Research Award applicants. Candidates must be a member of the SPR E2E Section.

This award must be applied for at the time of PAS abstract submission.

Eligibility Criteria

Be a SPR Emerging to Established (E2E) Section Member
Be a fellow-in-training (PhD post-doctoral fellows do not qualify)
Submit and present the abstract during the PAS Meeting prior to the completion of fellowship
Complete the online application form and submit their abstract and supplemental materials by the abstract submission deadline
The applicants need to describe their contribution to the project when asked to provide “brief description of the work performed”
The abstract must be basic research
First authorship on an abstract submitted to the PAS Meeting; the abstract must be accepted for presentation at the upcoming PAS Meeting to be considered
The recipient must present the study at the PAS Meeting

Applications that do not meet the conditions stated above will not be considered for the awards. The accuracy of your abstract and application is the applicants’ responsibility. Please proofread carefully before submitting. After submission, no corrections will be permitted. By submitting, you approve the accuracy of your abstract and application.

Current Recipients

Dr. Orgel is a physician-scientist in the Neonatal-Perinatal Medicine Fellowship program at the University of North Carolina (UNC) at Chapel Hill. Dr. Orgel received her MD/PhD from UNC, where she studied T cell and antibody responses in food allergies. Following her PhD and inspired by the premature birth of her daughter at 25 weeks gestation, her love of neonatal physiology, and her passion for caring for families in their most vulnerable moments, she decided to pursue a career in neonatology. Her research, with the mentorship of Dr. Misty Good, focuses on understanding the immunologic mechanisms that underly the development of necrotizing enterocolitis (NEC), a life-threatening intestinal disease that predominately affects premature infants.

There are major knowledge gaps in our understanding of the pathophysiology of NEC despite decades of research. The Good Lab previously demonstrated that the polyfunctional cytokine interleukin-22 (IL-22) protects against intestinal injury during NEC. However, IL-22 requires tight regulation, as it has the potential to induce a pro-inflammatory response through signal transducer and activator of transcription 3 (STAT3). Dr. Orgel’s research focuses on the regulation of IL-22 signaling by IL-22 binding protein (IL-22BP), a soluble inhibitory IL-22 receptor that inhibits binding of IL-22 to its receptor. Specifically, she studies the IL-22/IL-22BP signaling axis during intestinal development and NEC-induced inflammation using human intestinal organoids as well as mouse models of the disease. Thus far, her work has shown that recombinant IL-22 induces expression of the gene for IL-22BP (Il22ra2) in the intestine of neonatal mice during homeostasis but not during experimental NEC. Additionally, Il22ra2 is down-regulated during NEC-induced inflammation in the absence of IL-22 administration. Dr. Orgel’s future studies will focus on elucidating the mechanisms behind these findings and their implications for disease pathogenesis.

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Kelly Orgel, MD, PhD

University of North Carolina at Chapel Hill

Jeremy Sandgren is a 3rd year neonatology fellow at the University of Iowa with an interest in neonatal sepsis. During fellowship, he has studied the role of iron in infections caused by E. coli K1, a common cause of neonatal sepsis and meningitis. His work has built off previous work in the lab demonstrating that neonatal mice, with high iron availability, are more susceptible to E. coli K1 than adults, who have low amounts of available iron. Specifically, he found that knocking out certain secreted iron scavenging compounds, called siderophores, from E. coli K1, it is possible to dramatically reduce mortality caused by E. coli K1 in a mouse model of neonatal early-onset sepsis. These data led him to create a vaccine against one of these siderophores, enterobactin (entF). When this vaccine is administered to adult female mice, their offspring have reduced susceptibility to E. coli K1 infection. These data are exciting because they offer a potential vaccination strategy against E. coli early-onset sepsis. Jeremy is excited to be joining the University of Iowa as faculty in the summer, where he plans to study the long-term effects of early-life inflammation on cardiovascular function as a physician-scientist.

Person wearing glasses, a light blue dress shirt, and dark tie, smiling against a plain light background.

Jeremy Sandgren, MD, PhD

University of Iowa

2024 | Michael Cookson, MD, MHS, Children’s Hospital Colorado & University of Colorado, Aurora, CO
2024 | Gabriel Devlin, MD/CM, Children’s Hospital Los Angeles, CA
2024 | Nikita Kalluri, MD, Boston Children’s Hospital, Boston, MA
2024 | Jeremy Sandgren, MD, PhD, University of Iowa, Iowa City, IA
2023 | James Nugent, MD, MPH, Yale University School of Medicine, New Haven, CT
2023 | Rameshwar (Ram) Rao, MD PhD, Stanford University, Stanford, CA
2023 | Kevin G. Williams, MD, FAAP, University of Miami, Miller School of Medicine, Miami, FL
2023 | Mattie Wolf, MD, Emory University School of Medicine/Children’s Healthcare of Atlanta, Atlanta, GA
2022 | Leslie Doucette, MD, Johns Hopkins, Baltimore, MD
2022 | Thu Tran, DO, University of Texas Health Science Center, Houston, TX
2022 | Mausma Bawa, MD, Jacobs School of Medicine, University of Buffalo, Buffalo, NY
2022 | Elizabeth Salazar, MD, Children’s Hospital of Philadelphia, Philadelphia, PA
2021 | Senthil Velan Bhoopalan, MBBS, PhD, St. Jude Children’s Research Hospital, Memphis, TN
2021 | Josef Newman, MD, University of Miami Miller School of Medicine, Miami, FL
2021 | Vivek Shukla, MD, University of Alabama at Birmingham, Birmingham, AL
2021 | Mausma Bawa, MD, University at Buffalo, Buffalo, NY
2020 | Lila Nolan, MD, Washington University School of Medicine in St. Louis, St. Louis, MO
2020 | Vivek V. Shukla, University of Alabama at Birmingham, Birmingham, AL
2020 | Cara Slagle, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH
2020 | Christopher Thom, Children’s Hospital of Philadelphia, Philadelphia, PA
2019 | Jason M. Nagata, MD MSc, UCSF, San Francisco, CA
2019 | Fotios Spyropoulos, MD, Boston Children’s Hospital, Boston, MA
2019 | Michelle Starr, MD, University of Washington, Seattle, WA
2019 | Elizabeth Taglauer, MD PhD, Boston Children’s Hospital, Harvard Medical School, Boston, MA
2018 | Fredrick Dapaah-Siakwan, University of Miami Miller School of Medicine, Miami, Florida
2018 | Jennifer Davidson, UTHSC
2018 | Andrew Franklin, Northwestern University/Ann & Robert H Lurie Children’s Hospital
2018 | David Neil Matlock, Jr., University of Arkansas for Medical Sciences
2017 | Colm R. Breatnach, The Rotunda Hospital, Dublin, Ireland, Royal College of Surgeons in Ireland
2017 | Steven L. Ford, Baylor College of Medicine/Texas Children’s Hospital, Houston, TX
2017 | Geoffrey A. Preidis, Baylor College of Medicine & Texas Children’s Hospital, Houston, TX
2017 | Aaron Jeffrey T. Yee, University of Alabama at Birmingham, AL
2016 | Petter Bjornstad, Children’s Hospital Colorado and Barbara Davis Center for Childhood Diabetes, Aurora, CO
2016 | Shanlee Davis, Children’s Hospital Colorado/University of Colorado, Aurora, CO
2016 | Ashley L. Steed, Washington University in St. Louis, St. Louis, MO
2016 | Allison E. Zanno, Children’s Hospital of Philadelphia, Philadelphia, PA
2015 | Prem Fort, University of Alabama at Birmingham, Birmingham, AL
2015 | Laura Madore, Tufts Medical Center, Boston, MA
2015 | Pratik Parikh, University of Rochester, Rochester, NY
2015 | Annette Scheid, Floating Hospital for Children, Floating Hospital for Children, Tufts Medical Center, Boston, MA
2014 | Vishnu Priya Akula, Stanford University School of Medicine, Palo Alto, CA
2014 | Hitesh Deshmukh, University of Pennsylvania, Philadelphia, PA
2014 | Birju A. Shah, Women and Infants Hospital of Rhode Island, Providence, RI
2014 | Daniel T. Swarr, The Children’s Hospital of Philadelphia, Philadelphia, PA
2013 | Danielle E. Soranno, Children’s Hospital of Philadelphia, Philadelphia, PA
2013 | Peter M. Wolfgram, University of Wisconsin School of Medicine, Madison, WI