2025 Award Recipients

SPR Awards Recipients

Maureen Andrew Mentor Award

Victor Nizet, MD

UC San Diego School of Medicine

Victor Nizet, MD is Distinguished Professor and Vice Chair of Basic Research, Department of Pediatrics, and Distinguished Professor of Pharmacy & Pharmaceutical Sciences at the University of California, San Diego (UCSD). A graduate of Reed College, Dr. Nizet received his medical training at Stanford University, completed a Residency and Chief Residency in Pediatrics at Harvard University’s Children’s Hospital in Boston, and a Fellowship in Pediatric Infectious Diseases at the University of Washington’s Children’s Hospital in Seattle. At UCSD, he leads a large basic and translational research laboratory studying bacterial pathogenesis, innate immunity, and novel approaches to treatment of antibiotic-resistant pathogens and sepsis. He has authored over 560 peer-reviewed publications and collaborated with several biotechnology companies to develop novel antibiotic and immune-based therapies and vaccines.

Dr. Nizet is particularly interested in graduate, postdoctoral, and junior faculty training and interdisciplinary research program development. In his laboratory, he has trained over 60 postdoctoral fellows and 20 PhD students, and more than 30 of his former trainees now hold independent faculty positions conducting extramurally funded research. At UCSD he is the PI of the NIAID T32 Training Program in Infectious Diseases and co-PI of the NICHD T32 Training Program in Pediatric Clinical Pharmacology, both of which support postdoctoral scholars and clinical fellows, as well as co-PI of the NIAID R25 Raising Advancement and Parity for Infectious Diseases Researchers and Training Director for the NICHD K12 Child Health Research Career Development Award, both of which support junior faculty members. He is also on the leadership committees of the Medical Scientist Training Program, PharmD/PhD Program, IRACDA Postdoctoral Fellow Program, and the National Center for Leadership in Academic Medicine.

Dr. Nizet’s contributions have previously been recognized by the E. Mead Johnson Award for Research in Pediatrics from the Society for Pediatric Research, the DC White Award for Interdisciplinary Research and Mentoring from the American Society of Microbiology, Career Awards from the American Heart Association and American Lung Association, an NIH/NIAID Merit Award, and his election to the American Society for Clinical Investigation (ASCI), Association of American Physicians (AAP), American Association for Advancement of Science (AAAS), American Institute for Medical and Biological Engineering (AIMBE), American Academy of Microbiology (AAM), and the National Academy of Medicine (NAM).

Thomas A. Hazinski Distinguished Service Award

Shetal Shah, MD, FAAP

Maria Fareri Children’s Hospital, New York Medical College

The Society for Pediatric Research (SPR) is pleased to announce that Shetal Shah, MD, FAAP has been named the 2025 Thomas A. Hazinski Distinguished Service Award recipient. This prestigious award recognizes Dr. Shah’s outstanding service to SPR. Dr. Shah, a Professor of Neonatology in the Division of Neonatology, Stem Cell Liaison at the Maria Fareri Children’s Hospital of New York Medical College, is widely respected for his advocacy and contributions to advancing child health research.

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Society for Pediatric Research Award in Honor of E. Mead Johnson

Katherine Y. King, MD, PhD

Baylor College of Medicine and Texas Children’s Hospital

Katherine Y. King MD PhD is Professor of Pediatric Infectious Diseases at Baylor College of Medicine and Texas Children’s Hospital, where she is part of the faculty for the Stem Cells and Regenerative Medicine Center and serves as Co-Director of the BCM Medical Scientist Training Program. Dr. King received her BA in Biochemical Sciences from Harvard University and her MD and PhD degrees from Washington University in St. Louis. A board-certified pediatric infectious diseases physician, Dr. King’s research focuses on the molecular mechanisms by which inflammation affects blood and immune cell production and clonal competition by hematopoietic stem cells in the bone marrow.

Dr. King discovered that infections activate hematopoietic stem cell division. She showed that persistent hematopoietic stem cell division during chronic infectious and inflammatory conditions can drive bone marrow failure. Further, she showed that Inflammatory activation of hematopoietic stem cells contributes to clonal hematopoiesis, a condition associated with cardiovascular disease and other diseases of aging. This body of work has made a significant impact on explaining disease phenotypes such as why infections impede stem cell engraftment after transplant, and why immunotherapy patients develop persistent cytopenias.

Dr. King also showed that the intestinal microbiome is a critical mediator of normal hematopoiesis. She has defined key molecular pathways and bacterial species that may contribute to maintenance of the blood system. Defining the mechanisms of microbiome-dependent hematopoiesis will aid in prevention of chemotherapy and transplant-associated neutropenia.

Current work in the King lab is directed at how infections and inflammation may generate lasting epigenetic changes in hematopoietic stem and progenitor cells, providing innate immune memory. This work will uncover new ways to enhance innate immune function against emerging pathogens.

Dr. King has been the recipient of the NHLBI R35 Emerging Investigator Award and the Presidential Early Career Award for Scientists and Engineers (PECASE). She is a member of the Society for Pediatric Research, the American Pediatric Society, and the American Society for Clinical Investigation. Aside from her research, Dr. King has been an advocate for equity in access to care and inclusion in the biomedical sciences. She was a founder of the non-profit Doctors for Change, which advocated for improved access to care for people in Houston, and she was the 2024 recipient of the Leadership Award in Diversity, Equity, and Inclusion by the International Society for Experimental Hematology.

Douglas K. Richardson Award for Perinatal and Pediatric Healthcare Research

Grace M. Aldrovandi, MD, CM

UCLA Mattel Children’s Hospital

Dr. Grace Aldrovandi is a physician-scientist and Chief of the Division of Infectious Diseases at UCLA Mattel Children’s Hospital and a Professor of Pediatrics at the David Geffen School of Medicine of the University of California, Los Angeles. Dr. Aldrovandi received her undergraduate and her medical degree from McGill University in Montreal, Canada. She completed an internship and residency at McGill, as well as a research fellowship in pediatric infectious diseases at the University of California, Los Angeles.   She is a board-certified pediatric infectious diseases specialist with over 20 years experience in caring for both general pediatric infectious diseases as well as HIV infected children and their families. Dr. Aldrovandi’s research interests include pediatric HIV, the effects of breast milk on child health and infections in immunocompromised children. She has published more than 200 peer review publications in such journals as Nature, Journal of Virology, and the New England Journal of Medicine and multiple book chapters. She has been a member of many National Institutes of Health study sections and lectured throughout the world.

Dr. Aldrovandi has had continuous NIH funding for over 20 years, and in recognition of her significant contributions was honored with the prestigious Elizabeth Glaser Scientist Award. She and her collaborators were the first to describe increased morbidity and mortality among HIV-exposed uninfected infants, an essential discovery with potential implications for improving health outcomes in this vulnerable population. Dr. Aldrovandi’s laboratory is at the forefront of investigating microbial communities’ role in various compartments, ranging from mucosal (breast, vagina, rectum, oral) to non-mucosal (skin) regions. Their pioneering work demonstrated the presence of perturbations in the microbiome of infants born to HIV-infected women, despite the infants not being infected with HIV. Employing sophisticated bioinformatics approaches, they have skillfully modeled microbial maturation and strain transfer from breast milk to infant stool, unveiling new insights into this crucial area of research.

Having played prominent leadership roles in several NIH-funded clinical trials Networks, Dr. Aldrovandi has a deep understanding of the collaborative efforts essential for transformative research in the field. This unique perspective allows her to identify opportunities for innovative and impactful investigations

Dr. Aldrovandi is deeply committed to nurturing the next generation of scientists and has actively engaged in mentoring activities to encourage underrepresented Latino and African-American high school students to pursue careers in STEM fields. Her mentoring efforts have garnered attention and recognition, with a feature on Despierta America, highlighting the impact of their work in inspiring and guiding young minds towards scientific excellence. Moreover, Dr. Aldrovandi has had the privilege of mentoring numerous talented individuals, guiding them through their academic and research journeys. Her mentorship has been instrumental in helping these individuals secure prestigious awards and grants, including T32, K08, K23, K99, R01, and a Doris Duke Award.

Bridging to Success Award

PROSPER Diversity Award

Shannon Adams-Hartung, MD

Ann and Robert H. Lurie Children’s Hospital of Chicago

Dr. Shannon Adams-Hartung is a first-year fellow in the Division of Neonatology at Ann & Robert H. Lurie Children’s Hospital of Chicago. Born and raised in Baltimore, Maryland, she attended college at Duke University where she graduated cum laude, double majoring in History and Global Health. She then went on to receive her medical degree from the Warren Alpert Medical School of Brown University before completing her residency in pediatrics at the McGaw Medical Center of Northwestern University/Ann & Robert H. Lurie Children’s Hospital of Chicago.

Shannon’s academic interests lie at the intersection of neonatology and medical ethics, including topics in maternal-fetal management, neonatal end-of life decision making, prenatal counseling in the case of extreme prematurity or congenital anomaly, and health equity. As a medical student, she conducted research looking at parent and physician interpretations of quality of life for neonatal patients through the Scholarly Concentration in Medical Humanities and Ethics at Brown, and was later selected to participate in the interdisciplinary Fellowship at Auschwitz for the Study of Professional Ethics (FASPE). She continued her work in residency where she completed the McGaw Bioethics Scholars Program at Northwestern and engaged in research and writing related to the use of DNR orders in the NICU, abortion and perinatal palliative care provision in the wake of the Dobbs decision, and institutional culture on the topic of periviability. She is currently launching a multi-center mixed-methods study building on her previous ethical cultures work.

Evan Rajadhyaksha, MD

Indiana University School of Medicine

Evan is a first-generation American, shaped by a rich cross-cultural upbringing. His parents, who immigrated from opposite sides of the world, blended their cultures and instilled in him a deep pride in his identity as both Hispanic and Indian-American.

Evan completed his undergraduate and medical education at the University of Virginia (UVA), where his passion for immunology blossomed as he investigated the impact of allergic asthma on the innate immune response to rhinovirus. Staying at UVA for pediatric residency, he was drawn to the spectrum and complexity of diseases treated in nephrology. He chose to specialize in nephrology for the way it combines features of immunology and rheumatology with critical care physiology, while allowing for long-term patient relationships—one of his favorite aspects of pediatric medicine.

Now in his second year of pediatric nephrology fellowship at Indiana University, Evan continues to explore how immune responses can become maladaptive and cause harm. Through his T32 in clinical pharmacology, he has utilized single cell transcriptomics, developing a keen interest in applying gene expression and pathway analyses to pediatric nephrology research. The PROSPER award has significantly supported his project, which investigates the effect of Vitamin D deficiency on the immune response to pyelonephritis within the unique cellular microenvironment of the kidney, building on his previous research experiences.

New Member Outstanding Science Award

Amanda Muir, MD, MTR

Children’s Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania

Dr. Muir’s clinical and research goal is to improve the lives of children with eosinophilic gastrointestinal disease and prevent the devastating consequences of eosinophilic inflammation including weight loss feeding disorders, dysphagia and esophageal stricture.  Following training in general pediatrics,  a strong foundation in mucosal immunology led to a natural interest in pediatric gastroenterology, in which perturbations in the balance between environmental factors and host innate immune responses have a profound impact upon human growth and development. Among its many complications, disruptions in the esophageal epithelial homeostasis is the most striking histologic feature of eosinophilic esophagitis (EoE).  Dr. Muir has been able to grow expertise in esophageal epithelial biology and 3-D culture systems.  Using primary culture methods, she has developed an esophageal organoid platform to recapitulate the EoE microenviroment and has been able to utilize this model to understand the role of the esophageal epithelium in propagating inflammation and fibrosis.  She has been able to build a robust platform for biobanking, growing primary organoid, air liquid interface and organotypic cultures, and performing in depth genetic and transcriptomic evaluations.  In addition to this disease modeling in vitro, Dr. Muir also has a clinical research portion of her lab. A major knowledge gap in the field of EoE is how to identify esophageal fibrosis prior to the onset of a frank stricture. She has pioneered the use of a novel tool, the endoluminal function imaging probe or EndoFLIP, in clinical and research practice in the pediatric GI community. EndoFLIP uses high-resolution impedance planimetry to determine the pressure-geometry relationship or distensibility of the esophagus. Using this tool, she has found that EoE patients have decreased esophageal distensibility compared to healthy non-EoE controls. Furthermore, this difference is exacerbated by disease complications including esophageal fibrosis and food impactions.

SPR Awards to Enhance Diversity in the Research Workforce

Young Investigator Award

Daniel Corwin, MD, MSCE

Children’s Hospital of Philadelphia

Daniel Corwin, MD, MSCE is a Pediatric Emergency Medicine Attending Physician, Assistant Professor of Pediatrics at the Perelman School of Medicine at the University of Pennsylvania, Director of Clinical and Translational Research for the Division of Emergency Medicine at Children’s Hospital of Philadelphia (CHOP), Associate Director and Emergency Department Lead of the CHOP Minds Matter Program, and Scholar and Leadership Council Member for CHOP’s Center for Injury Research and Prevention. He completed his undergraduate work at the University of Pennsylvania, medical school at the New York University School of Medicine, and his pediatric residency, pediatric emergency medicine fellowship, and pediatric emergency medicine research fellowship at Children’s Hospital of Philadelphia.

His research focuses on: (1) improving mild traumatic brain injury (TBI) diagnosis across care settings, including utilizing objective physiologic markers of injury to facilitate timely and accurate diagnosis; (2) improving mild TBI risk stratification for pediatric patients evaluated shortly following injury, to appropriately guide referral and intervention strategies; (3) improving equity in TBI care by exploring novel care pathways, with a specific focus on digital health and remote patient monitoring as tools to optimize care equity; and (4) evaluating early therapeutics for mild TBI, including leading the first randomized trial of a nutraceutical to improve mild TBI symptoms in the pediatric population. His work is supported by grants from the NIH, CDC, BARDA, Department of Defense, and Toyota Way Forward Fund. The hallmark of his work is high quality research resulting in impactful peer-reviewed publications, coupled with translation and implementation of that research at the point-of-care.

SPR and APS Joint Award Recipient

Mary Ellen Avery Neonatal Research Award

Cynthia Bearer, MD, PhDCynthia Bearer, MD, PhD

Rainbow Babies & Children’s Hospital, Case Western Reserve University

Dr. Cynthia Bearer is the William & Lois Briggs Chair of Neonatology and Chief, Division of Neonatology, Rainbow Babies & Children’s Hospital and Professor of Pediatrics & Neurosciences at Case Western Reserve University. She has made significant contributions to neonatal health through basic and translational research for multiple conditions impacting the developing brain, such as fetal alcohol syndrome, hyperbilirubinemia, and toxic environmental exposures.

Press Release

FOPO Award Recipient

Joseph W. St. Geme, Jr. Leadership Award

James M. Perrin, MD
Massachusetts General Hospital, Harvard Medical School
Dr. James M. Perrin is the 2025 Joseph W. St. Geme, Jr. Leadership Award recipient. Dr. Perrin, an emeritus professor of pediatrics and academic general pediatrician at Mass General for Children (MGfC) and Harvard Medical School, is widely respected for his visionary leadership and commitment to advancing care for children and youth with special health care needs.

Press Release

Abstract Related Awards Recipients

House Officer Research Award

Student Research Award

Japan Pediatric Society (JPS)/SPR Fellows’ Exchange Award

Yuto Arai, MD, PhD

Division of Child Neurology, Department of Brain and Neurosciences, Faculty of Medicine, Tottori University

I am an Assistant Professor at Tottori University specializing in Child Neurology, with a focus on improving the quality of life for children with epilepsy and their families. I have previously developed a long-term prognostic model for Infantile Epileptic Spasms Syndrome, identified prognostic factors related to employment outcomes in childhood-onset drug-resistant epilepsy, and conducted studies on the subjective well-being of parents of children with disabilities.

This study is the first to demonstrate that climate change serves as a seizure trigger in children with drug-resistant epilepsy. These findings are expected to enhance the understanding of seizure triggers among patients’ families and healthcare providers, thereby contributing to improvements in epilepsy management.

This recognition underscores my commitment to advancing pediatric neurology and supporting families affected by epilepsy.

Ryo Nishiguchi, MD

NHO Nagasaki Medical Center

Ryo Nishiguchi is a neonatologist at NHO Nagasaki Medical Center in Japan. At the hospital, he is involved in daily neonatal care in the NICU and developmental care in the outpatient setting. His practice and research also focus on the long-term prognosis, including disease and development, of preterm and low-birth-weight infants.

He received his medical degree from Nagasaki University School of Medicine. He trained in neonatal medicine at the NICU of Saitama Medical Center, Saitama Medical University, one of the largest in Japan. He currently works as a neonatologist in his hometown of Nagasaki, where he lives with his wife and two sons.

Hisao Okabe, MD

Department of Pediatrics, School of Medicine, Fukushima Medical University

Over the past decades, our research team at the Department of Pediatrics, Fukushima Medical University has conducted a longitudinal study analyzing amino acid (AA) mutations in the fusion (F) protein of respiratory syncytial virus (RSV) and their effects on monoclonal antibody (mAb) sensitivity and viral replicative capacity. We analyzed 236 RSV strains isolated from children hospitalized with RSV infections between 2008 and 2023 in Fukushima Prefecture, Japan. Our team identified significant AA mutations in key neutralizing epitopes (sites II, V, and Ø) of the F protein. For instance, we discovered that mutations in site V and Ø influenced antibody sensitivity, without decreasing replicative capacity. Using neutralization assays and replication studies, we demonstrated that RSV in Japan naturally evolved with AA mutations that affect sensitivity to specific antibodies. Our findings highlight the importance of continuous monitoring of AA mutations to better understand their implications for antibody-based treatments and vaccine strategies. This award acknowledges the collective efforts and contributions of our team in advancing the understanding of RSV evolution, antibody resistance, and the clinical implications of these findings, with the hope of contributing to improved outcomes for pediatric patients worldwide.

European Society for Pediatric Research Young Investigator Exchange Award

Vincent Gaertner, MD, BSc

ILMU Hospital Munich

Vincent D. Gaertner, M.D., B.Sc., is a postdoctoral researcher in the neonatal division at the Dr. von Hauner Children’s Hospital in Munich, Germany. He graduated summa cum laude in medicine from the University of Regensburg, Germany, and in psychology from the University of Mannheim, Germany. His research led him to work at the Neonatal Departments of the University Hospital Zurich in Switzerland, and the Royal Women’s Hospital in Melbourne, Australia.

His scientific work focuses on the pathophysiology of fetal-to-neonatal transition, as well as different respiratory support strategies for very preterm infants immediately after birth and in high-risk situations in the neonatal intensive care unit. Now he is heading his own research group where he aims to improve our understanding of the physiology of neonatal transition and to improve respiratory support strategies in the delivery room and on the NICU.

He has received numerous awards including the Adalbert-Czerny medal from the German Society for Pediatrics. Currently, he received the Young Investigator Award of the European Society for Pediatric Research for the EAGLE study where he assessed lung volume changes during the first breaths after birth in healthy term-born infants using electrical impedance tomography. In this study, he described how quickly the newborn lung is aerated, how infants generate functional residual capacity after birth and how air is distributed during this crucial moment in life.

Fellows’ Basic Research Award (2 awards given annually)

Noor Mehandi, MD

University of Miami Miller School of Medicine

I am a second-year clinical fellow in the Neonatal-Perinatal Medicine Fellowship at the University of Miami Miller School of Medicine/Jackson Health System. To deepen my understanding of the pathogenesis of Bronchopulmonary dysplasia (BPD), I pursued a basic science research project under Dr. Shu Wu, focusing on the critical roles of inflammasome cascades in hyperoxia-induced lung injuries in neonatal mice.

Under Dr. Wu’s guidance, I spearheaded the investigation into the role of apoptosis associated speck-like protein containing a caspase recruitment domain (ASC) in BPD and the effects of IC100, a humanized anti-ASC antibody in preventing BPD in hyperoxia-induced mouse models. My first objective was to determine if hyperoxia activates ASC speck formation, which is required for inflammasome activation. I exposed ASC-citrine reporter mice, expressing ASC fusion protein with a C-terminal Citrine (fluorescent GFP isoform) to room air (RA) or 85% oxygen (O2) from postnatal day (P) 1 to P14, and then dissected the lung on P14, and prepared tissue sections for examination of ASC specks. I found that O2-exposed lungs had strong signals for ASC specks and BPD-like pathology, suggesting the activation of inflammasomes.

I then conducted experiments to assess the efficacy of IC100 in preventing hyperoxia-induced BPD. I randomized newborn mice to RA with placebo, RA with IC100 intraperitoneal injection, 85% O2 with placebo, and 85% O2 with IC100 intraperitoneal injection. On P14, I dissected the lung from these mice, assessed lung structures by radial alveolar count (RAC), and measured lung inflammation by counting macrophage infiltration in the alveolar airspace. I found that hyperoxia exposure reduced alveolarization and increased lung inflammation; however, IC100 treatment improved alveolarization and reduced lung inflammation in hyperoxia-exposed lungs. These results highlight the critical role of ASC in the pathogenesis of BPD and suggest that IC100 may have the potential to treat preterm infants from developing BPD.

Anusha Mopuri, MBBS, MD

UH Rainbow Babies and Childrens Hospital

Dr. Anusha Mopuri has been recognized for my innovative research in neonatal respiratory medicine, where she developed a novel approach using aerosolized human mesenchymal stem cell–conditioned media to prevent CPAP-induced airway hyperreactivity. Her work bridges basic science and clinical application, aiming to improve long-term respiratory outcomes in preterm infants.

David G. Nathan in Basic Research Award (1 award given annually)

Benjamin Fensterheim, MD, PhD

Children’s Hospital of Philadelphia

Developing new and effective therapies for preterm infants remains challenging, partly due to limited knowledge of how preterm birth alters normal immune system development. During my Neonatal-Perinatal Medicine fellowship, I aimed to precisely characterize how the preterm immune system evolves over time and in response to diseases of prematurity.

To achieve this, I established a pipeline to perform deep immune profiling using whole blood scavenged from the clinical laboratory every two weeks from preterm infants born in the Intensive Care Nursery at the Hospital of the University of Pennsylvania. I identified key immune cells and proteins whose development varied across gestational ages, and pinpointed immune pathways most affected by certain complications of prematurity. Notably, some preterm infants with severe infections had a dramatic shift in their CD8 T-cell composition, which persisted for months, and others with severe bronchopulmonary dysplasia showed progressive increases in CD4+ Th17 T-cell-related immune activity.

This project, which I conceptualized, executed, and analyzed, highlights how comorbidities of prematurity can change normal immune system development. It suggests specific immune mechanisms, such as the Th17 pathway, as potential drivers of disease progression, offering promising avenues for future therapeutic interventions.

Basic Research Award for Fellows, sponsored by the Emerging to Established (E2E) SPR Members’ Section (2 awards given annually)

Kelly Orgel, MD, PhD

University of North Carolina at Chapel Hill

Dr. Orgel is a physician-scientist in the Neonatal-Perinatal Medicine Fellowship program at the University of North Carolina (UNC) at Chapel Hill. Dr. Orgel received her MD/PhD from UNC, where she studied T cell and antibody responses in food allergies. Following her PhD and inspired by the premature birth of her daughter at 25 weeks gestation, her love of neonatal physiology, and her passion for caring for families in their most vulnerable moments, she decided to pursue a career in neonatology. Her research, with the mentorship of Dr. Misty Good, focuses on understanding the immunologic mechanisms that underly the development of necrotizing enterocolitis (NEC), a life-threatening intestinal disease that predominately affects premature infants.

There are major knowledge gaps in our understanding of the pathophysiology of NEC despite decades of research. The Good Lab previously demonstrated that the polyfunctional cytokine interleukin-22 (IL-22) protects against intestinal injury during NEC. However, IL-22 requires tight regulation, as it has the potential to induce a pro-inflammatory response through signal transducer and activator of transcription 3 (STAT3). Dr. Orgel’s research focuses on the regulation of IL-22 signaling by IL-22 binding protein (IL-22BP), a soluble inhibitory IL-22 receptor that inhibits binding of IL-22 to its receptor. Specifically, she studies the IL-22/IL-22BP signaling axis during intestinal development and NEC-induced inflammation using human intestinal organoids as well as mouse models of the disease. Thus far, her work has shown that recombinant IL-22 induces expression of the gene for IL-22BP (Il22ra2) in the intestine of neonatal mice during homeostasis but not during experimental NEC. Additionally, Il22ra2 is down-regulated during NEC-induced inflammation in the absence of IL-22 administration. Dr. Orgel’s future studies will focus on elucidating the mechanisms behind these findings and their implications for disease pathogenesis.

Jeremy Sandgren, MD, PhD

University of Iowa

Jeremy Sandgren is a 3rd year neonatology fellow at the University of Iowa with an interest in neonatal sepsis. During fellowship, he has studied the role of iron in infections caused by E. coli K1, a common cause of neonatal sepsis and meningitis. His work has built off previous work in the lab demonstrating that neonatal mice, with high iron availability, are more susceptible to E. coli K1 than adults, who have low amounts of available iron. Specifically, he found that knocking out certain secreted iron scavenging compounds, called siderophores, from E. coli K1, it is possible to dramatically reduce mortality caused by E. coli K1 in a mouse model of neonatal early-onset sepsis. These data led him to create a vaccine against one of these siderophores, enterobactin (entF). When this vaccine is administered to adult female mice, their offspring have reduced susceptibility to E. coli K1 infection. These data are exciting because they offer a potential vaccination strategy against E. coli early-onset sepsis. Jeremy is excited to be joining the University of Iowa as faculty in the summer, where he plans to study the long-term effects of early-life inflammation on cardiovascular function as a physician-scientist.

Fellows’ Clinical Research Award (3 awards given annually)

Richard D. Rowe Award in Clinical Research (1 award given annually)

Clinical Research Award for Fellows, sponsored by the Emerging to Established (E2E) SPR Members’ Section (2 awards given annually)