CONNECT.

Sat. May 5, 4-5:30pm - Celebration of Diversity & Inclusion Reception

Celebration of Diversity & Inclusion

You are cordially invited to the 2nd annual PAS reception to celebrate Diversity and Inclusion. Sponsored with AAP, APA, and APS.

Everyone Welcome!

Fairmont Hotel Library, Toronto Canada
Saturday, May 5, 2018
4:00pm ‚Äď 5:30pm

Mon., May 7, 7-8:30am - SPR Breakfast Session with NCATS, Office of Rare Diseases Research Director Dr. Ann R. Pariser

SPR Breakfast Session with NCATS, Office of Rare Diseases Research Director Dr. Ann R. Pariser

Dr. Ann R. Pariser, National Center for Advancing Translational Sciences National Institutes of Health

Mon, May 07
7:00 AM – 8:30 AM
Convention Center 501 AB

This session, led by Dr. Ann Pariser, will focus on NCATS’ innovative efforts to engage patients and their caregivers at every stage of the translational science spectrum. Examples of NCATS Research initiatives including Discovering New Therapeutic Uses for Existing Molecules, Tissue Chip for Drug Screening and the Office of Rare Diseases Research will be discussed from the perspective of how to address the multitude of translational science challenges facing both researchers and study participants.

Mon., May 7, 9-11:30am - SPR Presidential Scientific Plenary

SPR Presidential Scientific Plenary

Mon, May 07
9:00 AM – 11:30 AM
Convention Center 718 AB

Session Affiliations: Society for Pediatric Research

Presentations

9:00 AM
9:05 AM
Welcome
Michelle Gill, MD, PhD, President, Society for Pediatric Research, Associate Professor, Departments of Pediatrics and Immunology, Divisions of Infectious Diseases and Pulmonary Vascular Biology, UT Southwestern Medical Center, Dallas, TX

9:05 AM
9:07 AM
Introduction: SPR Young Investigator Award
Michelle Gill, UT Southwestern Medical Center

9:07 AM
9:19 AM
SPR Young Investigator Award & Lecture: “On The Causes of Childhood Cancer”
Alex Kentsis, MD, PhD, Assistant Professor of Pediatrics, Pharmacology, and Physiology & Biophysics, Weill Medical College of Cornell University, Memorial Sloan Kettering Cancer Center

9:19 AM
9:22 AM
Introduction: The SPR Award Given in Honor of E. Mead Johnson
Kate Ackerman, SPR Strategy & Operations Officer, University of Rochester School of Medicine, Rochester, NY, and Christina J. Valentine, Neonatologist/Medical Director, North America, IFCN, Reckitt Benckiser/Mead Johnson Nutrition

9:22 AM
9:34 AM
The SPR Award & Lecture Given in Honor of E.¬†Mead Johnson: “Human Monogenic¬†Immunodeficiency Diseases with Susceptibility to¬†Virus Infections”
Helen Su, MD, PhD, Senior Investigator and Chief of the Human Immunological Diseases Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health

9:34 AM
9:37 AM
Introduction: SPR New Member Outstanding Science
Michelle Gill, UT Southwestern Medical Center

9:37 AM
9:42 AM
SPR New Member Outstanding Science Lecture:¬†“Inflammation and Hematopoiesis”
Katherine Y.¬†King, MD, PhD, Baylor College of Medicine and Texas¬†Children’s Hospital

9:42 AM
9:45 AM
Introduction: SPR New Member Outstanding Science
Michelle Gill, UT Southwestern Medical Center

9:45 AM
9:50 AM
SPR New Member Outstanding Science Lecture:¬†‚ÄúThe Unbearable Lightness of Being‚ÄĚ
Indi Trehan, MD, MPH, DTM&H, Associate Professor of Pediatrics, Washington University in St. Louis, Medical Director, Lao Friends Hospital for Children

9:50 AM
9:54 AM
Introduction: SPR Physician Scientist Award
Cynthia Bearer, Editor-in-Chief, Pediatric Research, University of Maryland School of Medicine

9:54 AM
10:04 AM
SPR Physician Scientist Award & Lecture: ‚ÄúNovel¬†Gene Discovery in a Cohort of Patients with¬†Craniofacial and Neurologic Syndromes‚ÄĚ
Elizabeth Bhoj, MD, PhD, Children’s Hospital of¬†Philadelphia

10:04 AM
10:07 AM
Introduction: Runner-up of SPR Physician Scientist Award
Michelle Gill, UT Southwestern Medical Center

10:07 AM
10:17 AM
Runner-up of SPR Physician Scientist Award &¬†Lecture: ‚ÄúThe Nasopharyngeal Microbiome: a¬†Novel Target for Pneumonia Prevention?‚ÄĚ
Matthew S. Kelly, MD, MPH, Assistant Professor of Pediatrics, Duke University, Durham, NC

10:17 AM
10:37 AM
SPR Presidential Address: “The Journey to¬†Discovery: Lessons from Scientists, Leaders and¬†Children”
Michelle Gill, UT Southwestern Medical Center

10:37 AM
10:42 AM
Introduction: SPR Special Invited Speaker
Michelle Gill, UT Southwestern Medical Center

10:42 AM
11:12 AM
SPR Special Invited Speaker: “NIH National Center¬†for Advancing Translational Sciences and¬†Pediatric Research”
Anne R. Pariser, MD, Director, Office of Rare Diseases Research, National Institutes of Health, National Center for Advancing Translational Sciences

11:12 AM
11:30 AM
Closing
Michelle Gill, UT Southwestern Medical Center

Mon., May 7, 11:30am-1pm - SPR Awards Presentations and Luncheon

SPR Awards Presentations and Luncheon

Mon, May 07
11:30 AM – 1:00 PM
Convention Center 501 AB

11:30 AM
11:35 AM
Welcome
Michelle Gill, MD, President, Society for Pediatric Research, Associate Professor, Departments of Pediatrics and Immunology, Divisions of Infectious Diseases and Pulmonary Vascular Biology, UT Southwestern Medical Center, Dallas, TX

Presentations

11:35 AM
11:40 AM
Introduction and Presentation of Maureen Andrew Mentor Award
Valerie P. Opipari, MD, Chair, Pediatrics and Communicable Diseases, Ravitz Foundation Professor of Pediatrics and Communicable Diseases, Professor, Pediatric Hematology & Oncology, University of Michigan

11:40 AM
11:42 AM
Maureen Andrew Mentor Awardee
Jeffrey R.¬†Fineman, MD,¬†Professor and Vice Chair of Pediatrics, Chief, Division¬†Critical Care Medicine, Investigator, Cardiovascular¬†Research Institute, University of California, San¬†Francisco, UCSF Benioff Children’s Hospital

11:42 AM
11:45 AM
Introduction and Presentation of Thomas Hazinski Distinguished Service Award
Michelle Gill, UT Southwestern Medical Center

11:45 AM
11:47 AM
Thomas Hazinski Distinguished Service Awardee
Kate G. Ackerman, MD, Associate Professor, Division of Pediatric Critical Care, Dept. of Pediatrics, University of Rochester School of Medicine and Dentistry

11:47 AM
11:47 AM
SPR Physician Scientist Award Finalist
Lisa Bartnikas, Boston Children’s Hospital

11:47 AM
11:47 AM
SPR Physician Scientist Award Finalist
Pinar Gumus Balikcioglu, Duke University

11:47 AM
11:47 AM
SPR Physician Scientist Award Finalist
Natasha Hanners, UT Southwestern Medical Center

11:47 AM
11:48 AM
SPR Student Research Award
Jessica Thomson, Murdoch Children’s Research Institute

11:48 AM
11:49 AM
SPR Student Research Award
Rachel Shenoi, Baylor College of Medicine

11:49 AM
11:50 AM
SPR Student Research Award
Sydney Rooney, Vanderbilt University School of Medicine

11:50 AM
11:51 AM
SPR Student Research Award
Jennifer Varner, Duke University Medical Center

11:51 AM
11:52 AM
SPR Student Research Award
Sietske Berghuis, Beatrix Children’s Hospital, University Medical¬†Center Groningen, University of Groningen

11:52 AM
11:53 AM
SPR Student Research Award
Hannah Itell, Duke University Medical Center

11:53 AM
11:54 AM
SPR House Officer Research Award
Joseph Alge, Baylor College of Medicine

11:54 AM
11:55 AM
SPR House Officer Research Award
Colm Travers, UAB Hospital

11:55 AM
11:56 AM
SPR House Officer Research Award
Stephanie Davis-Rodriguez, Cincinnati Children’s Hospital¬†Medical Center

11:56 AM
11:57 AM
SPR Junior Section Fellow Research Award
Fredrick Dapaah-Siakwan, University of Miami Miller School of Medicine

11:57 AM
11:58 AM
SPR Junior Section Fellow Research Award
Andrew Franklin, Northwestern University/Ann & Robert H¬†Lurie Children’s Hospital

11:58 AM
11:59 AM
SPR Junior Section Fellow Research Award
Jennifer Hendrick, University of Tennessee

11:59 AM
12:00 PM
SPR Junior Section Fellow Research Award
David Matlock, University of Arkansas for Medical Sciences

12:00 PM
12:01 PM
SPR Fellow Basic Science Research Award
Abbie Bauer, University of Washington

12:01 PM
12:02 PM
SPR Fellow Basic Science Research Award
Steven Jonas, University of California, Los Angles

12:02 PM
12:03 PM
SPR Fellow Basic Science Research Award
Kathleen Schwabenbauer, Children’s Hospital of Pittsburgh of¬†UPMC

12:03 PM
12:04 PM
SPR Fellow Clinical Research Award
Anne Fuller, Children’s Hospital at Montefiore, Albert Einstein¬†College of Medicine

12:04 PM
12:05 PM
SPR Fellow Clinical Research Award
Megan Griffiths, Johns Hopkins

12:05 PM
12:06 PM
Japan Fellow Exchange Program Award
Kimino Fujimura, Shin-Yurigaoka General Hospital

12:06 PM
12:07 PM
Japan Fellow Exchange Program Award
Hironori Shibata, Keio University School of Medicine ÔĄÖ
12:07 PM
12:08 PM
Japan Fellow Exchange Program Award
Toshihiko Suzuki, Nagoya University Hospital

12:08 PM
12:09 PM
European SPR Young Investigator Exchange Program Award
Nathalie Claessens, Wilhelmina, Children’s Hospital, University¬†Medical Center Utrecht

12:09 PM
12:10 PM
SPR Travel Awards to Enhance Diversity in the Research Workforce: Eastern SPR Award
Suhasini Kaushal, MedStar Georgetown University Hospital

12:10 PM
12:11 PM
SPR Travel Awards to Enhance Diversity in the Research Workforce: Midwest SPR Award
Courtney Rowan, Indiana University School Of Medicine

12:11 PM
12:12 PM
SPR Travel Awards to Enhance Diversity in the Research Workforce: Southern SPR Award
Rolando Macias, University of Texas Health Science Center San Antonio

12:12 PM
12:13 PM
SPR Travel Awards to Enhance Diversity in the Research Workforce: Western SPR Award
Viviana Fajardo, University of California Los Angeles

12:13 PM
12:14 PM
Douglas K. Richardson Award
Bonnie Ramsey, Seattle Children’s

12:14 PM
12:15 PM
APS/SPR Mary Ellen Avery Neonatal Research Award
Richard Martin, Rainbow Babies & Children’s Hospital

12:15 PM
12:16 PM
David G. Nathan Award in Basic Research Award
Julie Nogee, Washington University School of Medicine

12:16 PM
12:17 PM
Richard D. Rowe Award for Clinical Research Award
Catherine Buck, Brown University

12:17 PM
12:17 PM
Eastern SPR (ESPR) Faculty Award
Raul Chavez-Valdez

12:17 PM
12:17 PM
Eastern SPR (ESPR) Fellow Award
Sharina Rajbhandari, New York Medical College; Maria Fareri¬†Children’s Hospital at Westchester Medical Center

12:17 PM
12:17 PM
Midwest SPR (MWSPR) Frederic M. Kenney Award for Outstanding Fellow or Resident
Stacy Kern, University of Iowa Hospitals and Clinics

12:17 PM
12:17 PM
Midwest SPR (MWSPR) Jack Metcoff Award for Outstanding Resident or Fellow
Katie Satrom, University of Minnesota

12:17 PM
12:17 PM
Midwest SPR (MWSPR) James Sutherland Award
Jennifer Bermick, University of Michigan

12:17 PM
12:17 PM
Midwest SPR (MWSPR) James Sutherland Awards
David Gordon, University of Iowa

12:17 PM
12:17 PM
Midwest SPR (MWSPR) Council Award
Haley Bremer, Columbia University

12:17 PM
12:17 PM
Midwest SPR (MWSPR) Stanley Phillips Award
June Hu, Washington University in St. Louis School of Medicine

12:17 PM
12:17 PM
Midwest SPR (MWSPR) William Segar Award
John Feister, Nationwide Children’s Hospital

12:17 PM
12:17 PM
Southern SPR (SSPR) Young Investigator Award (Clinical Research)
Erynn Bergner, Baylor College of Medicine, Texas Children’s¬†Hospital

12:17 PM
12:17 PM
Southern SPR (SSPR) Young Investigator Award (Basic Science)
Mohamed Khass, University of Alabama-Birmingham

12:17 PM
12:17 PM
Western SPR (WSPR) Abbott Nutrition Young Investigator Award
Alison Chu, University of California Los Angeles

12:17 PM
12:17 PM
Western SPR (WSPR) Abbott Nutrition Pediatric Trainee Research Award
Brianna MacQueen, University of Utah

12:17 PM
12:22 PM
Closing
Michelle Gill, UT Southwestern Medical Center

COLLABORATE.

Sat., May 5, 8-10am - SPR Research Toolbox: Hands-On Practical Workshop on Genetic and Genomics Tools to Study Human Health and Disease

SPR Research Toolbox: Hands-On Practical Workshop on Genetic and Genomics Tools to Study Human Health and Disease

Sat, May 05
8:00 AM – 10:00 AM
Convention Center 703

Session Tracks: Academic and Research Skills, Basic Science, Bioinformatics/Proteomics, Developmental Biology, Genetics
Session Affiliations: American Academy of Pediatrics, American Pediatric Society, Society for Pediatric Research
Target Audience: Child health researchers or clinicians with an interest in: Human Genetics, Research in Genetics including model organisms, Developmental Biology, and Precision Medicine.
Objectives: 1. Describe tools and tips for learning more about human disease candidate genes 2. Describe database resources and tools for various model organisms including the Alliance of Genome Resources and Mouse Genome Informatics 3. To practice using the tools introduced in the workshop by going through a set of real examples including examples brought by the audience.

In this workshop, the presenters will guide audience through various topics including discovery of candidate genes associated with human diseases or sets of phenotypes and potential mouse models of human disease. The Human-Mouse Disease Connection (HMDC) portal will be presented, which is part of Mouse Genome Informatics (http://www.informatics.jax.org) database. The MGI database is an expert curated open sourced database that integrates genetic, genomic, phenotype, functional, expression, and disease data to provide comprehensive biological information for users. MGI also includes link out to various resources and databases on our pages. The new Alliance of Genome Resources (http://www.alliancegenome.org) will also be presented with updates about current and future developments planned for that resource. Audience will learn easy-to-use tools to expedite discovery of candidate genes for disease or to identify what a gene does with easy to understand information.

Attendees are encouraged to bring their laptop or tablet to follow along. The audience will work on examples that require using online tools on human genetics and gene set analysis. Attendees are encouraged to bring their own diagnostic genetic puzzles and favorite genes to this workshop.

Session Chairs
Workshop Co-Leader
Kate Ackerman, University of Rochester Medical Center
Workshop Co-Leader
David Shaw, The Jackson Laboratory

Sat., May 5, 10:30am-12pm - PAS Opening General Session and Keynote Speaker/Joseph St. Geme Leadership Award

PAS Opening General Session and Keynote Speaker/Joseph St. Geme Leadership Award

Sat, May 05
10:30 AM – 12:00 PM
Convention Center 718 AB

Session Affiliations: American Academy of Pediatrics, Academic Pediatric Association, American Pediatric Society, Society for Pediatric Research, PAS Labs

Session Chair
Chair
Thomas Shanley,¬†Lurie Children’s Hospital of Chicago

Presentations

10:30 AM
10:35 AM
PAS Welcome
Thomas Shanley, Lurie Children’s Hospital of Chicago

10:35 AM
Joseph W. St. Geme, Jr. Leadership Award –¬†Recipient: Mark Schuster, MD, PhD

10:55 AM
11:00 AM
Introduction of Debbie Anagnostelis Keynote Address
Thomas Shanley, Lurie Children’s Hospital of Chicago

11:00 AM
11:45 AM
Debbie Anagnostelis Keynote Address: The Triumph of Human Spirit
Roberto Canessa, Italian Hospital of Montevideo

11:45 AM
11:50 AM
Closing Remarks
Thomas Shanley, Lurie Children’s Hospital of Chicago

Mon., May 7, 3:30-5:30pm - SPR Research Toolbox: Implementing Transcriptomics into Translational Research in Children

SPR Research Toolbox: Implementing Transcriptomics into Translational Research in Children

Mon, May 07
3:30 PM – 5:30 PM
Convention Center 717 A

Session Tracks: Academic and Research Skills, Basic Science
Session Affiliations: Society for Pediatric Research, Pediatric Infectious Diseases Society
Target Audience: This workshop is open to students, residents, fellows, faculty and other researchers interested in learning principles relevant to transcriptomics research in children.
Objectives: ‚ÄĘ Plan appropriate experimental designs for observational or interventional clinical¬†studies utilizing transcriptomics ‚ÄĘ Recognize the methods/assays employed for RNA sample¬†collection and processing considerations in transcriptomics research, with a focus on utilizing¬†minimally invasive samples and small blood volumes ‚ÄĘ Gain new insights into the analytical tools¬†and bioinformatics approaches used in transcriptomics research.

Whole-genome transcriptional profiling (transcriptomics) is a powerful approach to identify novel biomarkers and mechanisms of human diseases. Of all the systems-scale molecular profiling technologies available, genomic approaches are the most comprehensive and robust. Transcriptional profiling accurately reflects both dynamic changes in cellular composition and cellular response during the course of disease. Transcriptomics has become an essential tool in conducting clinical and translational research at all levels including hypothesis generation, defining disease mechanisms and signaling pathways, identification of disease markers and risk assessment, and monitoring response to interventions.

This interactive session will introduce a basic understanding of study design and methods of transcriptional profiling and systems scale data analysis that can be applied to clinical and translational studies with specific focus on pediatric populations. By providing specific clinical questions and examples, the first hour will focus on practical considerations of sample collection,  methodologies for profiling, and experimental design considerations. The second hour will focus on selecting and implementing suitable methods for data analysis and results interpretation and will include interactive demonstrations. At the end of this workshop attendees will be able to identify the optimal type of samples suitable for transcriptional profiling, the main tenets  for designing and applying transcriptomics into a clinical study, and the optimal methods and tools for data processing and analyses.

Session Chairs
Workshop Co-Leader
Matthew Altman, University of Washington
Workshop Co-Leader
Asuncion Mejias